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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc436141f5450832b5f320a12b86cb07af463661a1dbe1ef3759065a51be437' 
  AND token = '20iy4n7qdB+AtJiiRI1BLVsy8Adjx5PvuVaUCFZERZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}