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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e69b62465a80626c154512ab78c2455f4ba3f4b486a06cc7eb670cd7f60bf9' 
  AND token = 'Nn7cDkOvOHJOOaMW/iLjLlyfJTUYuETwf5310xjAobI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}