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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1944886f51f2831544e0285dd5e723c9d0c2216dc36e502c18db82dada26909' 
  AND token = '12i1R5EexmeCQ2j/fq+8JUSSy0oSpKs/R381nEuxvZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}