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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d7c9df2437cc848c77fd26c3d0316687ab301c49ba3fff47a794baf43e11fb6' 
  AND token = 'Q6e0i59t2u0zDqqL9F8xYNDqh+QdoXxQ0C/rEFoC8is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}