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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a159f6c7c0586b15a270983c879cf955c6e4ff50b8aa193b010f87356fe255f7' 
  AND token = 'uxxn3WRvsdVOgi88tpsCAEecin1o1F2GfaNPx0G1zqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}