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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b1c33464c2c0f747d5c94b998024aad6cf4b181e80119e6efc2e2dbcf4bcc3' 
  AND token = 'iwlo65nwKqP0Jxr+wTidQFucR5TyFaRmRudg60Q6I4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}