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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff5365971ad71bbad08135b5600de61cb74a20f9584880b637c5ac0ff1cade9b' 
  AND token = '0dmg1MdH4EhRzccF/Ib0NpeOQqKFQ0Faci8Y+WEU2sY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}