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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7acfe5c2d291d3c749e3a77a572a4a965d88939cf10498e3da0c8cc94336c90b' 
  AND token = 'WwtFwLGVrdybSF1SjTZ1l1AEitw55A/1+wJyc4nM8Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}