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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b45ef39e5deb35b418a17558d45d88ba9f0db3264c42af3e09ba044f02d5d177' 
  AND token = 'sPZZz9myWY2zLLstx1tbQJ4ITprk3HOoHoA0u5Hdd4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}