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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa22323b17819d4e7334eabe9c981d72c7de7f3aebed9037619a17371a3cc4b2' 
  AND token = '5Fh+2o8EF4xoCCpBRbmXGWVGwjaQm1rWmZdKftBjqDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}