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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4491ad24f5f1bcc4ed5fb2cb41ece2bbd63ceee9631dbd22cca8a3d7ee2ce81' 
  AND token = 'lWuwmRNkdPiJkHX3NvVaA1dN4S+gHfLtEHdjvvEvP7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}