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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '878642f7b25efddc222f044caf6366b6c44ed7628ed125656966929545ac1a67' 
  AND token = 'n+5zcRjlMbR/lxEmKwp/HjDz1dt1vsv7duPeBZ5mFHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}