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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0feeb2cd853af366e70d7447703e021ca184b59b1c5c80f96f2a994714c67458' 
  AND token = 'eStely6q5XEpw82rNbY0AvSAqmST4xoahltALIU8uAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}