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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d41269034bf59827d11903c4a319c5cb9a8cad3bd337107e9f9425f348d0447' 
  AND token = 'HO/CNH664RCTXDb3porzH4pH1AXf0/G3nauKMXOhn78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}