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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a1f9b91e7afe6ce6f4039539d983d17e827b26a47ecdebc3f7ee7905a16e9f' 
  AND token = '25rDcEKhcJK9/APuKXC2qlEJ8DVZfXRFEkebZxNQv40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}