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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49446f958f759c39f2f9f5ef4102b39103b1d3142086b4827884c994e6da935' 
  AND token = '4SrRO3WiGfwlv3G3y3jmGNTAlimm9FdqFTe+Vpn+Hjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}