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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f3fd320614502c10f69b67efbf040ce0215d47ea1cfd7c21d0d0f13e6ebf78' 
  AND token = 'klK6l0phMgMXQCVTde0rmeKq/C0NzBJ35IFWfmocDmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}