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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '342209cf652c7614ee87342a0b2bfb5b119159f657ef5bcda363dc929fd165d6' 
  AND token = 'Ot6o1gtOfohhT5T7dpkO5eEyB9G8sEEoPvBCEcPJ76Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}