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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd9caca7a6b78f1e68690b4a6cb0fddcb496b79549fbc37b02316032b5b051e' 
  AND token = 'EgKtew4NlAKZyDDWITwOPBSVIX+pUMOFLdDdJelU1IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}