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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd1c74a58e5d5d033f36758535981fcd743e0ade5230ac3823fb446e0c2d1cf4' 
  AND token = 'HAVs+xAVQ24RpPfiSfgtorw3tNtEWqnWwmkqaAcVejk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}