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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d3074ca9e72dd7ef69d54ff2c2bedbdc0e74f829b43fc25a14d569806916b2' 
  AND token = 'unWKHbIpQpq/VkCxfrtwOLitC/To5053phLk/QzzCwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}