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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ad04f1b93780fbe80b6fb9025900ac78e80200db2b2b39b929e4178c37048b' 
  AND token = 'LC3DOaM7OXmWpslxpjvj5B5u88IExPMxu5asYmL49Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}