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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '816361ec2109e869f2c5e8b8e16b09694ea0f6a75e9dbaae009a3653d83401f3' 
  AND token = 'zWCUOoM42tKCF0+YCWC+lkik+20cO1FXHNW5cqXFuSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}