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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69782750f10c6bc15843b1e7571cf8ab1ad67360c9d9da05610a91edfd49c030' 
  AND token = '28koUEDJNRsIvCbJMDkjhysULzYFDUzP+RN8W5Zj9WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}