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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2955563a2139641f422d4d1bdf0216fd030d192758e2c2aebcc9fa3485b0090' 
  AND token = 'twIoBve/XUIHqaBt3UUapTNz1oz2CQANbA6+8jauDpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}