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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149f07b2af75d381aea2919bf2ac5976722e5a45a0be46a3af4642a951d72900' 
  AND token = 'FCc6tKVSC5q5bKR9gaOOVVEfL4wE8IP+ppfWvzqeYns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}