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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d45e050c4afaabf738fef57d2afdba70fb5edfa2ffab396a8cb69395c6715b' 
  AND token = '5Sw8e7NUsfTLZTN7wRh0WMypVKUzZAQBi5u5rhyssXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}