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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c0e90080c6fc44b4147d2c1ac952faa2ef0043afc27a00de3cb60137cbc2799' 
  AND token = 'tq6PMdYhpTzrp/jqtPuk2L2gT6nujmNxbL9PsY2X5HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}