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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a760f9ab49350124c3ca906657c9f874f015580c1ddd374019b28ec72c1008' 
  AND token = 'YRIiGC9YozmK6GqZ9MNdw3LPw2DqhEbuaHna+4xxy2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}