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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e521896871f26ae38b3d237a8686b43485d6af049e9fc25796954502bae2fb' 
  AND token = '1CGWoTeEjbq5K6sFdCbodNboNB6hywwafQeucJMjjF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}