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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de800028b6007248dc1e7ad4b181819fef7d938093df816847c8a05034077bad' 
  AND token = 'qIJH+jFpqF5RtI5fU50e0T8mU0yH6KiS3jse4F34L2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}