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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7728dc510b892ed08902a4320622a031e868b5eabb07c4d2d46ee8641b8b6bcc' 
  AND token = 'wJNGONWbwwY2M0xGcfbVG8P8i2NeV9P2HgFUIVrbWOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}