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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c812b366bc65640c02011e8f214e577b9759fca8705fa2b8f3c231383a4991ce' 
  AND token = 'hn8OOlpEkqqXsa42rkMnFp+RF9vG8Z/XWpafr43lez4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}