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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c0231356fce85d429bf1ae0685bd6d6ae7405cebc5381f5f39a22b1f9c3fe8' 
  AND token = 'DZzRevgUjpacsOpBm+6Fhf9tdBZXJ45BnLcbT9VUgv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}