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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e25c486555090cafadfd3db25e3c739d624ef69fd3dbd35b5b5a8285719c9b' 
  AND token = 'jGRScS20CoGor7qRD580cI4wHf0Ec1IMG4OgE1xC/G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}