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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1b6ea7e105d8b44bafd6be78a73d8ffd43462d6d2f0395f5351bfc9faff59a' 
  AND token = 'ubXZqmyfT/gLNJwA03WSlX7PQteitFKe3AbhpYAZpIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}