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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d8e04dbd15788eb5f35e06cac85c8d8e6214a8eb11cc4b777ac563ede962a8' 
  AND token = 'OCg4z51MWgJT1ZPCvHxWQgQmoKmXdVHPm8E581QZhS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}