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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44efc4128b0200b6bafb0a8c6c48e393975072de1336c46231355dbc7911a7a6' 
  AND token = 'meHNbhcgfgF4E+T2MGy4V8hM7gGmxPVXKNvgRcH0r4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}