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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e9541344cad3b75661c3a5f1eda31964bc9fcb12edfcc932d72a360e8f6278d' 
  AND token = 'kWDTCu481R/CVJOfd0aiTtGh3ziekuDi/AGhQgrgRDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}