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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdbb5177029392630ec5c46b74438d18036e58ee6388f0d89002d81f981a14d3' 
  AND token = 'OQSUW3hCKT9bjS805SE1pLuGQmWNfLY+EOL6IRXAF1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}