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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca659eb5a65f5765a004b1979c9604ef6006f5fad71049a44bc5acab9c417db' 
  AND token = '1GglMOkRhDV+DW2Tf4DthwmpZkb5mabdv2LkkB+erAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}