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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73219b95d210e2b0e1a5a873e0420ca0021d13e1898b0ad9fd81f37a5706b1a2' 
  AND token = 'yaS3oH/7nfY6mBUN5NkRbgz1uU8RBZch0pWNOENIfho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}