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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d731c35d1037b14035cc61e0f14be3c5126b4b80575b1fc7cb284df56aa100' 
  AND token = 'go48lvs2J0gPYTAhJJkrulHowNPvYID5Dm71aIbsyZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}