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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1815664968c55f31ed002d9c22ab7a59956b1128fd2e0c6236c8fcc863d34ce7' 
  AND token = 'i8rg0F6tsHnXRU0S8I7UIiKN0kfNKyGy4IrkEv4k0PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}