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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea614e28538c19769a8bc8c52c7970c4d3b5361658c61f7136ba419509f294d' 
  AND token = '852pZTEN+EsHWs/urZWGwU44x25NxGU1kbppSqP+n9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}