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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea4b599e735054ad3f3ae5952f12fe3357282e25ea408b4ef4df727fb9e1365' 
  AND token = 'K75KQm79K8FpMFEXeTAGnaWG8Wa1e+3iv/jE3mnqEYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}