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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe99167f9c3d94d181b9191d1c570b9ac2b81fc7011caf50fc7c6b8a018fa87d' 
  AND token = 'GeQAi1kkuBg+y4uheKfN8+0PVoj2v/OOf07rhDgIDo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}