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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0373edc57e31925c381c5b3b527fd61a04e051ba9ca2fc27d57bb8a0b2b02b6e' 
  AND token = 'KBiDGj1NFu9ujH3g9wgdN85Pg5Uo8cZYiURAJns+YOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}