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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f436827a915ab5b3e0de1cf394dcbdf0558dde1a4b9c0498d39a30791a1d1cbf' 
  AND token = 'u1li4OvA2QhABC0IMcfRM4zeGeA7R7LGDWfq7vbJwPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}