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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21872d8a1c517aa1e3bd4231142ac02b245ff1a6763a26acc6059d44b9fb7b66' 
  AND token = 'm8pa7zlcllIYqjRaX3quLZVOdrh7oOT8CNVfskGUhmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}